Biodegradable Polylactide Supraparticle Powders with Functional Additives for Biomedical Additive Manufacturing

Additive manufacturing, in particular powder bed-based fabrication processes hold promise to revolutionize biomedical engineering for the ability provide customized, functional implants, example as bone replacement materials. However, providing particles that unify material requirements biodegradable and bioactive biomaterials process enable successful bed fusion remains an unmet challenge. Here, a supraparticle-based approach create poly(lactic acid) composite powders additive manufacturing of materials is introduced. Colloidal binary Ca-SiO2 glasses hydroxyapatite are incorporated additives support formation bone-like calcium phosphate. The supraparticle prepared by scalable spray-drying process, which offers control particle size, shape, composition. All process-relevant characteristics analyzed function composition structure, including flowability, thermal, melt rheological properties. optimized successfully used laser polymers prepare macroscopic specimens via manufacturing. It demonstrated combination composites provides relevant properties, biodegradation bioactivity. flexible adjustable toolbox design toward